Fks1 activity
WebDec 22, 2013 · Structural analyses revealed that the FKS1 mutant biofilms that were produced by the caspofungin-resistant FKS1 mutant were generally less dense, with a predominance of yeast and pseudohyphae... WebMay 30, 2024 · Furthermore, through isolation of a mutant resistant to micafungin from a micafungin-sensitive erg mutant and genetic analysis of it, we found that the responsible mutation occurred in the hotspot 2 of FKS1 encoding β-1, 3-glucan synthase, indicating that micafungin inhibited the growth of the erg mutant via inhibiting Fks1 activity.
Fks1 activity
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WebMar 23, 2024 · Figure 1. Schematic diagram of the three-dimensional structure of FKS1. More importantly, the research team successfully mapped out the important mutations affecting FKS1 activity as well as the key purification and reaction conditions, and successfully established an efficient and reproducible in vitro reaction system for FKS1 … WebJan 10, 2024 · The genes ERG11, ERG3, TAC1 and GSC1 ( FKS1) in C. albicans, as well as ERG11, CgPDR1, FKS1 and FKS2 in C. glabrata were sequenced. Results Fifty-four different missense mutations were identified, 13 of which have not been reported before.
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WebOct 22, 2024 · In vitro activity was determined for 89 Candida glabrata isolates with … WebJun 22, 2009 · The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. C. Douglas, F. Foor, +7 authors M. El-Sherbeini Biology Proceedings of the National Academy of Sciences of the United States of America 1994
WebDec 20, 1994 · These results suggest that FKS1 encodes a subunit of 1,3-beta-D-glucan …
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