Itsn1-ot1
Web18 okt. 2007 · He et al. (2007) showed that mammalian Wnk1 ( 605232) and Wnk4 ( 601844) interacted with Itsn1 and that these interactions were crucial for stimulation of Romk1 (KCNJ1; 600359) endocytosis. Stimulation of Romk1 endocytosis by Wnk1 and Wnk4 required their proline-rich motifs, but it did not require their kinase activities. WebIntersectin-1 is a protein that, in humans, is encoded by the ITSN1 gene. Function. The protein encoded by this gene is a cytoplasmic membrane-associated protein that …
Itsn1-ot1
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WebITSN1 (ITSN, MGC134948, MGC134949, SH3D1A, SH3P17) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. ITSN1. SECTIONS. TISSUE BRAIN SINGLE CELL TYPE TISSUE CELL TYPE WebThe major isoform ITSN1-s is monoubiquitinated, whereas the minor one, ITSN1-22a undergoes a combination of mono- and oligoubiquitination. The monoubiquitination is required for ITSN1-s stability, whereas the oligoubiq-uitination of ITSN1-22a causes its proteasomal degradation. This explains the observed low abundance of the minor …
Web20 okt. 2024 · Introduction Ulcerative colitis (UC), a subtype of inflammatory bowel disease (IBD), is characterized by chronic and relapsing mucosal inflammation initiating in the rectum and extending upward through part or the entire colon in a continuous fashion ( 1 ). The worldwide prevalence of UC has increased in the last few decades. Web@article{Zong2024AtractylodisMP, title={Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1.}, …
Web1 feb. 2024 · Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1. X. Zong, Xiao Xiao, +6 authors M. … Web27 feb. 2013 · Invertebrate studies have highlighted a role for EH and SH3 domain Intersectin (Itsn) proteins in synaptic vesicle recycling and morphology. Mammals have two Itsn genes ( Itsn1 and Itsn2 ), both of which can undergo alternative splicing to include DBL/PH and C2 domains not present in invertebrate Itsn proteins. To probe for specific …
Web15 jan. 2024 · We observed that ITSN1-OT1 was the most altered lncRNA among these upregulated lncRNAs involved in the tight junction (Fig. 5 D), although it is not the …
Web4 mei 2024 · Studies have shown that Atractylodis macrocephalae polysaccharides can affect phosphorylated-STAT2 into the nucleus through lncRNA ITSN1-OT1, thus resisting the damage of Dextran sulfate sodium to intestinal epithelial cells (Zong et al. 2024). c l franklin my favorite sermonsWeb11 aug. 2024 · SAM68 is an mRNA-binding protein involved in mRNA processing in the nucleus that forms membraneless compartments called SAM68 Nuclear Bodies (SNBs). We found that intersectin 1 (ITSN1), a multidomain scaffold protein harboring five soluble SH3 domains, interacts with SAM68 proline-rich motifs (PRMs) surrounded by self-adhesive … c. l. franklin shotWeb24 okt. 2024 · This study aimed to evaluate the predictive value of long non-coding RNA intersectin 1-2 (lnc-ITSN1-2) for acute ischemic stroke (AIS) risk, and investigate its correlation with disease severity, inflammation, and recurrence-free survival (RFS) in AIS patients. Methods clf react with kbrWebA two-stage analysis of rare de novo and inherited coding variants in 42,607 ASD cases, including 35,130 new cases from the SPARK cohort, in Zhou et al., 2024 identified … bmw black roundelWebMechanistically, we identified a novel lncRNA ITSN1-OT1, which was induced by RAMPtp during DSS stimulation. It blocked the nuclear import of phosphorylated STAT2 to … bmw black roofWeb15 jan. 2024 · Mechanistically, we identified a novel lncRNA ITSN1-OT1, which was induced by RAMPtp during DSS stimulation. It blocked the nuclear import of phosphorylated … clfreestreamsWeb28 okt. 2024 · ITSN1 gene (intersectin 1) is located on chromosome 21q22.11 and encodes a cytoplasmic membrane-associated protein involved in many cellular processes such as … c l franklin hannah the ideal mother