Siglec 10 antibody

WebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane protein that has four extracellular Ig-like domains, a transmembrane region, and a cytoplasmic tail with two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (2). WebProduct Specific Information. Mouse anti Human Siglec-10 antibody, clone 5G6 recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and …

WO2024085166A1 - Siglec-10 antibodies - Google Patents

WebSIGLEC10 antibody LS-C325111 is an unconjugated rabbit polyclonal antibody to human SIGLEC10 (aa667-695). Validated for ELISA and WB. Products. Research Areas. COVID-19. Resources. ... SIGLEC10 SIGLEC-10 Siglec-like gene 2 Siglec-like protein 2 PRO940 SLG2. See All SIGLEC10 Antibodies. Host. Rabbit. WebThe amounts of HMGB1 associated with CD24Fc were determined by immunoblotting with anti-HMGB1 monoclonal antibody. The data shown are ... the CD24/Siglec-10 interaction has been ... how does the payback method work https://jsrhealthsafety.com

Siglec-10 Protein - ACROBiosystems

WebSiglec-G is the apparent ortholog of human Siglec-10 (4). The human Siglec-10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a 534 aa … WebAPC anti-human Siglec-10 Antibody. Human peripheral blood lymphocytes were stained with CD19 FITC and Siglec-10 (clone 5G6) APC (top) or mouse IgG1, κ APC isotype … WebSiglec-10 Fc (Mouse IgFc) at 10 μg ml was incubated with anti-Siglec-10 antibodies and the Siglec-10Fc/antibody complexes were incubated with tumor cell lines and then washed. … how does the pell grant work

Anti-SIGLEC10 antibody produced in rabbit affinity isolated …

Category:Development of Effective Siglec-9 Antibodies Against Cancer

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Siglec 10 antibody

Siglec-10 (E1D7S) XP® Rabbit mAb Cell Signaling Technology

WebTested in Western Blot (WB), Immunoprecipitation (IP) and ELISA (ELISA) applications. This antibody reacts with Human, Rat samples. Supplied as 200 µL purified antibody (0.5-1.5 … WebApr 14, 2024 · SiglecG is the apparent ortholog of human Siglec10 (4). The human Siglec10 cDNA encodes a 697 amino acid (aa) precursor that includes a 16 aa signal sequence, a …

Siglec 10 antibody

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WebHigh-quality Siglec-10 proteins from ACROBiosystems. Various species and tags of Siglec-10 proteins. Minimal Batch-to-Batch Variation. Bulks in stock. Login Register. Bulk order. Clear ... Antibodies Anti-idiotypic antibody Anti-FMC63 mAb … Websialic acid binding Ig like lectin 10 , PRO940 , SIGLEC-10 , SLG2 ... WB analysis of OVCAR-3 cells using GTX45910 SIGLEC10 antibody at 0.2-1μg/ml. REFERENCE. There are currently …

WebNov 29, 2024 · Summary. Siglec-9 is an immune checkpoint target and an immunoinhibitory receptor that can engage either sialic acid ligands or agonistic antibodies. Through Siglec … WebExpression of SIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use …

WebSiglec-10 Fc (Mouse IgFc) at 10 μg ml was incubated with anti-Siglec-10 antibodies and the Siglec-10Fc/antibody complexes were incubated with tumor cell lines and then washed. Selected antibodies blocked the binding of Siglec-10 … WebBuy rabbit polyclonal antibody to SIGLEC10 (A54002). Applications: ELISA, IP and WB. Reactivity: Human and Rat. ️ Low Prices ️ 100% Guarantee. Useful Links. 01223 298 ...

Web1 day ago · Although the exact role of Siglec-1 in the context of HIV-1 infection is still an area of active ... more convenient antibody treatments. Apr 13, 2024. T cells: Vesicles strengthen immune response.

WebClone 5G6 recognizes the sialic acid-binding Ig-like lectin 10 (Siglec-10) antigen, a member of the CD33-related group of siglecs. The cytoplasmic tail of Siglec-10 contains four … how does the patriarchy affect menWebRabbit SIGLEC10 Rabbit pAb (A20413), validaed in WB and tested in Human,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. … how does the pay period workWebWe offer Siglec-10 Antibodies for use in common research applications: Blockade of Receptor-ligand Interaction, ELISA, Flow Cytometry, Immunohistochemistry, … how does the pawn capture in chessWebJul 31, 2024 · The blockade of Siglec-10 using monoclonal antibodies augmented the phagocytic ability of macrophages, thereby confirming a role for Siglec-10 in inhibiting … photoelectron spectroscopy pdfWebJun 10, 2024 · High infiltration of Siglec-10 hi TAMs was associated with impaired CD8 + T cell function in HCC. Of note, blocking Siglec-10 with the competitive binding antibody … how does the paw paw fruit workLike most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more how does the pcm detect a cylinder misfireWebIn one embodiment, an anti-Siglec-9 antibody has a KD of about 1×10 −7 M to about 1×10 −10 M, about 1×10 −8 M to about 1×10 −10 M, or about 1×10 −9 M to about 1×10 −11 M, … photoelectron spectroscopy faraday discussion